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Reading: Nasal spray that reverses opioid overdoses approved for over-the-counter sales in Mississippi
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Reading: Nasal spray that reverses opioid overdoses approved for over-the-counter sales in Mississippi
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Featured NewsLatest NewsLifestyle

Nasal spray that reverses opioid overdoses approved for over-the-counter sales in Mississippi

Caleb Salers
By Caleb Salers February 1, 2024
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1 Min Read
OPVEE
OPVEE (submitted photo)
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An additional overdose-reversal remedy has received approval to be sold without a doctor’s prescription in Mississippi.

The state health department, in its efforts to reduce overdose fatalities, recently updated its standing order to include nalmefene, an opioid antagonist, in addition to naloxone as a viable method to protect individuals at risk of overdosing.

RELATED: Mississippi Bureau of Narcotics working to slow overdose fatalities 

Nalmefene, sold under the brand name OPVEE, is indicated for emergency treatment of known or suspected overdose induced by natural or synthetic opioids — such as fentanyl.

OPVEE is an FDA-approved nasal spray that is easy to use in a quick manner. Health experts recommend a single spray of the medication into one of the nostrils of any patient suspected to be overdosing.

Each bottle of the OPVEE contains one spray’s worth of the substance. Additional units of OPVEE can be used every two to five minutes if a patient does not respond.

MSDH now offering free overdose-reversing kits to residents

Copyright 2025 SuperTalk Mississippi Media. All rights reserved.

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By Caleb Salers
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Caleb Salers is a multimedia journalist for SuperTalk Mississippi News. As a lifelong Jacksonian, Caleb has deep roots in Mississippi and a vested interest in the Magnolia State. Prior to joining the news team, Caleb served as a podcast host. In his spare time, you will find Caleb watching sports, cheering on the Pittsburgh Steelers and Memphis Grizzlies. For inquiries or story tips, email [email protected].

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